Publications

Alzheimer’s Disease: Reflection and Hope

Francisco J. Vizoso
Asociación Alzheimer Asturias, Jan. 2026

Secretome from Uterine Cervical Mesenchymal Stem Cells as a Protector of Neuronal Cells Against Oxidative Stress and Inflammation

Javier Mateo, Miguel Ángel Suárez-Suárez, María Fraile, Ángel Ramón Piñera-Parrilla, Francisco J. Vizoso, Noemí Eiro
Biomolecules 2025
DOI: 10.3390/biom15101402
PMID: 41154631

Limitations and challenges in the characterization of extracellular vesicles from stem cells and serum

Sara Escudero-Cernuda, Noemi Eiro, María Fraile, Francisco J Vizoso, Belén Fernández-Colomer, María Luisa Fernández-Sánchez
Mikrochim Acta. 2025
DOI: 10.1007/s00604-025-07147-4
PMID: 40259021

Mesenchymal Stem Cells and Their Derived Products in Ageing and Diseases

Francisco J Vizoso, Luis A Costa, Noemi Eiro
Int J Mol Sci . 2024
DOI: 10.3390/ijms25136979
PMID: 39000084

Synergistic effect of human uterine cervical mesenchymal stem cell secretome and paclitaxel on triple negative breast cancer

Noemi Eiro, María Fraile, Sara Escudero-Cernuda, Juan Sendón-Lago, Luis O González, María Luisa Fernández-Sánchez, Francisco J Vizoso
Stem Cell Res Ther. 2024
DOI: 10.1186/s13287-024-03717-0
PMID: 38664697

New era of mesenchymal stem cell-based medicine: basis, challenges and prospects

Francisco J Vizoso, Luis A Costa, Noemi Eiro
Rev Clin Esp (Barc). 2023
DOI: 10.1016/j.rceng.2023.11.002
PMID: 38000623

Towards a New Concept of Regenerative Endodontics Based on Mesenchymal Stem Cell-Derived Secretomes Products

Luis A Costa, Noemi Eiro, Andrea Vaca, Francisco J Vizoso
Bioengineering (Basel) . 2022
DOI: 10.3390/bioengineering10010004
PMID: 36671576

Mesenchymal (Stem) Stromal Cells Based as New Therapeutic Alternative in Inflammatory Bowel Disease: Basic Mechanisms, Experimental and Clinical Evidence, and Challenges

Noemi Eiro, María Fraile, Alberto González-Jubete, Luis O González, Francisco J Vizoso
Int J Mol Sci. 2022
DOI: 10.3390/ijms23168905
PMID: 36012170

In Vivo Effects of Conditioned Medium from Human Uterine Cervical Stem Cells in an Ovarian Cancer Xenograft Mouse Model

Juan Sendon-Lago , Samuel Seoane, Fatima Saleh, Lucía Gacía-Caballero, María E Arias, Noemi Eiro, Manuel Macía, Francisco J Vizoso, Roman Perez-Fernandez, Jose Schneider
Cancer Genomics Proteomics. 2022
DOI: 10.21873/cgp.20341
PMID: 35985689

Conditioned Medium from Human Uterine Cervical Stem Cells Regulates Oxidative Stress and Angiogenesis of Retinal Pigment Epithelial Cells

Noemi Eiro, Juan Sendon-Lago , Sandra Cid, Jorge Saa, Nagore de Pablo, Belén Vega, María A Bermudez, Roman Perez-Fernandez , Francisco J Vizoso
Ophthalmic Res. 022
DOI: 10.1159/000524484
PMID: 35584686

Mesenchymal Stem/Stromal Cells and Their Derivates in Acute Diseases: Emergency in the Post-COVID-19 Times

Juan Sendon-Lago , Lorena Garcia-Del Rio , Noemi Eiro , Patricia Diaz-Rodriguez , Leandro Avila , Luis O Gonzalez , Francisco J Vizoso , Roman Perez-Fernandez , Mariana Landin
Int J Mol Sci. 2021
DOI: 10.3390/ijms22168395
PMID: 34445102

Tailored Hydrogels as Delivery Platforms for Conditioned Medium from Mesenchymal Stem Cells in a Model of Acute Colitis in Mice

Juan Sendon-Lago , Lorena Garcia-Del Rio , Noemi Eiro , Patricia Diaz-Rodriguez , Leandro Avila , Luis O Gonzalez , Francisco J Vizoso , Roman Perez-Fernandez , Mariana Landin
Pharmaceutics. 2021
DOI: 10.3390/pharmaceutics13081127
PMID: 34452089

Mesenchymal Stem Cell-Based Therapy as an Alternative to the Treatment of Acute Respiratory Distress Syndrome: Current Evidence and Future Perspectives

Silvia Fernández-Francos , Noemi Eiro , Natalia González-Galiano , Francisco J Vizoso
Int J Mol Sci. 2021
DOI: 10.3390/ijms22157850
PMID: 34360616

Importance of the origin of mesenchymal (stem) stromal cells in cancer biology: “alliance” or “war” in intercellular signals

Noemi Eiro , Maria Fraile , Silvia Fernández-Francos , Rosario Sánchez , Luis A Costa , Francisco J Vizoso
Cell Biosci. 2021
DOI: 10.1186/s13578-021-00620-6
PMID: 34112253

Mesenchymal Stem Cells as a Cornerstone in a Galaxy of Intercellular Signals: Basis for a New Era of Medicine

Silvia Fernández-Francos , Noemi Eiro , Luis A Costa , Sara Escudero-Cernuda , María Luisa Fernández-Sánchez , Francisco J Vizoso
Int J Mol Sci. 2021
DOI: 10.3390/ijms22073576
PMID: 33808241

The Coronavirus Pandemic (SARS-CoV-2): New Problems Demand New Solutions, the Alternative of Mesenchymal (Stem) Stromal Cells

Eiró N, Cabrera J, Fraile M, Costa L, Vizoso FJ
Front. Cell Dev. Biol., 2020
DOI: 10.3389/fcell.2020.00645
PMID: 32766251

Mesenchymal Stem Cells in Homeostasis and Systemic Diseases: Hypothesis, Evidences, and Therapeutic Opportunities

Vizoso FJ, Eiró N, Costa L, Esparza P, Landín M, Díaz-Rodríguez P, Schneider J, Pérez-Fernández R
Int J Mol Sci. 2019
DOI: 10.3390/ijms20153738
PMID: 31370159

Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses

Costa L, Eiró N, Fraile M, González L, Saá J, García-Portabella P, Vega B, Schneider J, Vizoso FJ
Cell Mol Life Sci, 2021
DOI: 10.1007/s00018-020-03600-0
PMID: 32699947

Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine

Vizoso FJ, Eiró N, Cid S, Schneider J, Pérez-Fernández R
Int J Mol Science 2017
DOI: 10.3390/ijms18091852

Corneal regeneration by conditioned medium of human uterine cervical stem cells is mediated by TIMP-1 and TIMP-2. Experimental Eye Research

Sendon-Lago J, Seoane S, Martinez-Ordoñez A, Eiro N, Saa J, Vizoso FJ, Gonzalez F, Perez-Fernandez R, Bermudez MA.
Experimental Eye Research 2019
DOI: 10.1016/j.exer.2018.12.004
PMID: 30557571

Antifungal Activity of the Human Uterine Cervical Stem Cells Conditioned Medium (hUCESC-CM) Against _Candida albicans_ and Other Medically Relevant Species of _Candida_ . Frontiers in Microbiology

Schneider J, Mateo E, Marcos-Arias C, Eiró N, Vizoso F, Pérez-Fernández R, Eraso E, Quindós G.
Front. Microbiol. 2018
DOI: 10.3389/fmicb.2018.02818
PMID: 30519227

Non Pregnant Human Uterus as Source of Mesenchymal Stem Cells. Current Stem Cell Research & Therapy

Eiro N, Fraile M, Schneider J, Vizoso FJ.
Current Stem Cell Research & Therapy 2018
DOI: 10.2174/1381612824666180426120459
PMID: 29701160

Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine

Vizoso FJ, Eiró N, Cid S, Schneider J, Perez-Fernandez R.
International Journal of Molecular Sciences 2017
DOI: 10.3390/ijms18091852
PMID: 28841158

Human Uterine Cervical Stromal Stem Cells (hUCESC): Why and How they Exert their Antitumor Activity

Schneider J, Eiró N, Pérez-Fernández R, Martínez-Ordóñez A, Vizoso F
Cancer Genomics Proteomics, 2016
PMID: 27566652

Anti-inflammatory effect of conditioned medium from human uterine cervical stem cells in uveitis

Bermudez MA, Sendon-Lago J, Seoane S, Eiro N, Gonzalez F, Saa J, Vizoso F, Perez-Fernandez R
Experimental Eye Research 2016
DOI: 10.1016/j.exer.2016.06.022
PMID: 27381329

Corneal epithelial wound healing and bactericidal effect of conditioned medium from human uterine cervical stem cells.

Bermudez MA, Sendon-Lago J, Eiro N, Treviño M, Gonzalez F, Yebra-Pimentel E, Giraldez MJ, Macia M, Lamelas ML, Saa J, Vizoso F, Perez-Fernandez R.
Invest Ophthalmol Visual Science.2015
DOI: 10.1167/iovs.14-15859
PMID: 25613942

Potential therapeutic effect of the secretome from human uterine cervical stem cells against both cancer and stromal cells compared with adipose tissue stem cells

Eiró N, Sendon-Lago J, Seoane S, Bermúdez MA, Lamelas ML, Garcia-Caballero T, Schneider J, Perez-Fernandez R, Vizoso FJ.
Oncotarget. 2014
DOI: 10.18632/oncotarget.2530
PMID: 25296979