A continuación se enumeran las investigaciones que han sido publicadas en revistas científicas y que muestran el potencial terapeútico del secretoma obtenido de las hUCESCs

Potential therapeutic effect of the secretome from human uterine cervical stem cells against both cancer and stromal cells compared with adipose tissue stem cells. Oncotarget.

  • Eiró N, Sendon-Lago J, Seoane S, Bermúdez MA, Lamelas ML, Garcia-Caballero T,  Schneider J, Perez-Fernandez R, Vizoso FJ.
  • 2014 Nov 15;5(21):10692-708 (Oncotarget)
  • PMID: 25296979
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Corneal epithelial wound healing and bactericidal effect of conditioned medium from human uterine cervical stem cells. Invest Ophthalmol Vis Sci.

  • Bermudez MA, Sendon-Lago J, Eiro N, Treviño M, Gonzalez F, Yebra-Pimentel E, Giraldez MJ, Macia M, Lamelas ML, Saa J, Vizoso F, Perez-Fernandez R.
  • 2015 Jan 22;56(2):983-92. (Investigative ophthalmology and visual science)
  • PMID: 25613942.
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Anti-inflammatory effect of conditioned medium from human uterine cervical stem cells in uveitis. Exp Eye Res.

  • Bermudez MA, Sendon-Lago J, Seoane S, Eiro N, Gonzalez F, Saa J, Vizoso F, Perez-Fernandez R
  • 2016 Aug;149:84-92. (Experimental Eye Research)
  • PMID: 27381329.
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Human Uterine Cervical Stromal Stem Cells (hUCESCs): Why and How they Exert their Antitumor Activity. Cancer Genomics Proteomics.

  • Schneider J, Eiró N, Pérez-Fernández R, Martínez-Ordóñez A, Vizoso F
  • 2016 09-10;13(5):331-7. Review. PubMed (Cancer Genomic and Proteomics)
  • PMID: 27566652.
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Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine. International Journal of Molecular Sciences

  • Vizoso FJ, Eiró N, Cid S, Schneider J, Perez-Fernandez R.
  • Int J Mol Sci. 2017 Aug 25; 18 (9). (International Journal of Molecular Science)
  • PMID: 28841158
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Non Pregnant Human Uterus as Source of Mesenchymal Stem Cells. Current Stem Cell Research & Therapy

  • Eiro N, Fraile M, Schneider J, Vizoso FJ.
  • 2018;13(6):423-431 (Current Stem Cell Research & Therapy)
  • PMID: 29701160.
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Antifungal Activity of the Human Uterine Cervical Stem Cells Conditioned Medium (hUCESC-CM) Against _Candida albicans_ and Other Medically Relevant Species of _Candida_ . Frontiers in Microbiology

  • Schneider J, Mateo E, Marcos-Arias C, Eiró N, Vizoso F, Pérez-Fernández R, Eraso E, Quindós G.
  • 2018 Nov 21;9:2818 (Frontiers in Microbiology)
  • PMID: 30519227.
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Corneal regeneration by conditioned medium of human uterine cervical stem cells is mediated by TIMP-1 and TIMP-2. Experimental Eye Research

  • Sendon-Lago J, Seoane S, Martinez-Ordoñez A, Eiro N, Saa J, Vizoso FJ, Gonzalez F, Perez-Fernandez R, Bermudez MA.
  • 2018 Dec 15;180:110-121 (Experimental Eye Research)
  • PMID: 30557571.
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Mesenchymal Stem Cell Secretome: Toward Cell-Free Therapeutic Strategies in Regenerative Medicine

  • Vizoso FJ, Eiró N, Cid S, Schneider J, Pérez-Fernández R
  • Int J Mol Science 2017 Aug 25;18(9):1852. doi: 10.3390/ijms18091852
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Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses

  • Costa L, Eiró N, Fraile M, González L, Saá J, García-Portabella P, Vega B, Schneider J, Vizoso FJ
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Mesenchymal Stem Cells in Homeostasis and Systemic Diseases: Hypothesis, Evidences, and Therapeutic Opportunities

  • Vizoso FJ, Eiró N, Costa L, Esparza P, Landín M, Díaz-Rodríguez P, Schneider J, Pérez-Fernández R
  • 2019 Jul 31;20(15):3738. doi: 10.3390/ijms20153738.
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The Coronavirus Pandemic (SARS-CoV-2): New Problems Demand New Solutions, the Alternative of Mesenchymal (Stem) Stromal Cells

  • Eiró N, Cabrera J, Fraile M, Costa L, Vizoso FJ
  • Front. Cell Dev. Biol., 16 July 2020
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Mesenchymal Stem Cells as a Cornerstone in a Galaxy of Intercellular Signals: Basis for a New Era of Medicine

  • Silvia Fernández-Francos , Noemi Eiro , Luis A Costa , Sara Escudero-Cernuda , María Luisa Fernández-Sánchez , Francisco J Vizoso
  • Int J Mol Sci. 2021 Mar 30;22(7):3576. doi: 10.3390/ijms22073576.
  • PMID: 33808241
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Importance of the origin of mesenchymal (stem) stromal cells in cancer biology: "alliance" or "war" in intercellular signals

  • Noemi Eiro , Maria Fraile , Silvia Fernández-Francos , Rosario Sánchez , Luis A Costa , Francisco J Vizoso
  • Cell Biosci. 2021 Jun 10;11(1):109. doi: 10.1186/s13578-021-00620-6.
  • PMID: 34112253
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Mesenchymal Stem Cell-Based Therapy as an Alternative to the Treatment of Acute Respiratory Distress Syndrome: Current Evidence and Future Perspectives

  • Silvia Fernández-Francos , Noemi Eiro , Natalia González-Galiano , Francisco J Vizoso
  • Int J Mol Sci. 2021 Jul 22;22(15):7850. doi: 10.3390/ijms22157850.
  • PMID: 34360616
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Tailored Hydrogels as Delivery Platforms for Conditioned Medium from Mesenchymal Stem Cells in a Model of Acute Colitis in Mice

  • Juan Sendon-Lago , Lorena Garcia-Del Rio , Noemi Eiro , Patricia Diaz-Rodriguez , Leandro Avila , Luis O Gonzalez , Francisco J Vizoso , Roman Perez-Fernandez , Mariana Landin
  • Pharmaceutics. 2021 Jul 23;13(8):1127. doi: 10.3390/pharmaceutics13081127.
  • PMID: 34452089
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Mesenchymal Stem/Stromal Cells and Their Derivates in Acute Diseases: Emergency in the Post-COVID-19 Times

  • Juan Sendon-Lago , Lorena Garcia-Del Rio , Noemi Eiro , Patricia Diaz-Rodriguez , Leandro Avila , Luis O Gonzalez , Francisco J Vizoso , Roman Perez-Fernandez , Mariana Landin
  • Int J Mol Sci. 2021 Aug 5;22(16):8395. doi: 10.3390/ijms22168395.
  • PMID: 34445102
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Conditioned Medium from Human Uterine Cervical Stem Cells Regulates Oxidative Stress and Angiogenesis of Retinal Pigment Epithelial Cells

  • Noemi Eiro, Juan Sendon-Lago , Sandra Cid, Jorge Saa, Nagore de Pablo, Belén Vega, María A Bermudez, Roman Perez-Fernandez , Francisco J Vizoso
  • Ophthalmic Res. 022;65(5):556-565.  doi: 10.1159/000524484. Epub 2022 May 18.
  • PMID: 35584686
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In Vivo Effects of Conditioned Medium from Human Uterine Cervical Stem Cells in an Ovarian Cancer Xenograft Mouse Model

  • Juan Sendon-Lago , Samuel Seoane, Fatima Saleh, Lucía Gacía-Caballero, María E Arias, Noemi Eiro, Manuel Macía, Francisco J Vizoso,  Roman Perez-Fernandez, Jose Schneider 
  • Cancer Genomics Proteomics. 2022 Sep-Oct;19(5):570-575. doi: 10.21873/cgp.20341.
  • PMID: 35985689 PMCID: PMC9353723
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Mesenchymal (Stem) Stromal Cells Based as New Therapeutic Alternative in Inflammatory Bowel Disease: Basic Mechanisms, Experimental and Clinical Evidence, and Challenges

  • Noemi Eiro, María Fraile, Alberto González-Jubete, Luis O González,  Francisco J Vizoso
  • Int J Mol Sci. 2022 Aug 10;23(16):8905. doi: 10.3390/ijms23168905.
  • PMID: 36012170 PMCID: PMC9408403
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Towards a New Concept of Regenerative Endodontics Based on Mesenchymal Stem Cell-Derived Secretomes Products

  • Luis A Costa, Noemi Eiro, Andrea Vaca,  Francisco J Vizoso
  • Bioengineering (Basel) . 2022 Dec 20;10(1):4. doi: 10.3390/bioengineering10010004.
  • PMID: 36671576 PMCID: PMC9854964
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New era of mesenchymal stem cell-based medicine: basis, challenges and prospects

  • Francisco J Vizoso, Luis A Costa, Noemi Eiro
  • Rev Clin Esp (Barc). 2023 Dec;223(10):619-628. doi: 10.1016/j.rceng.2023.11.002. Epub 2023 Nov 23.
  • PMID: 38000623
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Synergistic effect of human uterine cervical mesenchymal stem cell secretome and paclitaxel on triple negative breast cancer

  • Noemi Eiro, María Fraile, Sara Escudero-Cernuda, Juan Sendón-Lago, Luis O González, María Luisa Fernández-Sánchez, Francisco J Vizoso
  • Stem Cell Res Ther. 2024 Apr 25;15(1):121. doi: 10.1186/s13287-024-03717-0.
  • PMID: 38664697 PMCID: PMC11044487
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